Of the many constituents found in urine, one of them is creatinine. Basically, creatinine is a by-product released during the metabolism of creatine that is carried out in the muscles. The liver produces creatine which is used by the muscles during bodily movement. The waste matter (creatinine) that is generated on a daily basis has to be eliminated from the body. Our human body has a mechanism by which creatinine is eventually filtered from the blood and thrown out of the body. This has been discussed below.
Low creatinine in urine can be one of the symptoms of kidney diseases. This is because an important function of the kidneys involves removing surplus creatinine from the blood and then eliminating it through the urine. However, if this task is not being done efficiently, do not expect creatinine levels both in blood and urine to be normal. In the context of kidney disorders, urine creatinine normal range is a distant possibility.
When the kidneys are affected with some sort of disease, creatinine in blood increases substantially and that of urine dips dramatically. This indicates that the kidneys are not in a position to regulate creatinine levels in blood and urine. Their ability to remove creatinine in required amounts decreases considerably.
Poor functioning of the kidneys is reflected in poor concentration of creatinine in urine. Thus, one can say that creatinine blood or urine test is a barometer of our kidney's health. Assessing kidney function is possible after examining the results of creatinine test. Some of the kidney disorders associated with low creatinine levels in urine are given below:
The filtration of blood in the kidneys is done by a group of capillaries known as glomeruli. When these capillaries, that do the job of removing the impurities from blood, get swollen the condition is referred as glomerulonephritis. The inflammation can restrict the ability of the kidneys to extract creatinine.
This is a urinary tract infection that has traveled from the bladder and penetrated the kidneys. In simple words, pyelonephritis refers to a kidney infection resulting from invasion of E.coli bacteria. This form of bacterial infection affecting the kidneys can slow down the filtration process, leading to build up of creatinine in blood.
Acute Tubular Necrosis
Nephrons, very small tube-shaped cells in the kidneys, also help to remove waste matter from the blood. When these tubule cells of the kidneys get damaged, creatinine levels rise in the blood. Trauma, such as an accident that damages the kidneys, or extremely low blood pressure for at least half an hour causes acute tubular necrosis.
Poor Blood Circulation
It is a known fact that every organ in the body, including the kidneys, require sufficient blood supply in order to work properly. So, if enough blood is not being circulated to the kidneys, that can occur due to a wide range of reasons such as uncontrolled diabetes, dehydration and congestive heart failure (CHF), it can have a negative impact on the blood filtration process, leading to low creatinine in urine.
On the whole, low creatinine is something that cannot be taken lightly. It pin points towards progressive kidney damage, and hence consulting a doctor and taking necessary treatment should be your first priority.